Open AccessCrystal Structures of Phosphodiesterases 4 and 5 in Complex with Inhibitor 3-Isobutyl-1-methylxanthine Suggest a Conformation Determinant of Inhibitor Selectivity
Author(s) -
Qing Huai,
Yudong Liu,
Sharron H. Francis,
Jackie D. Corbin,
Hengming Ke
Publication year - 2004
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/6xnd-fd71
Subject(s) - phosphodiesterase , phosphodiesterase inhibitor , chemistry , stereochemistry , selectivity , pharmacology , biochemistry , biology , enzyme , catalysis