Open AccessDynamic Dysfunction in Dihydrofolate Reductase Results from Antifolate Drug Binding: Modulation of Dynamics within a Structural State
Author(s) -
Randall V. Mauldin,
Mary J. Carroll,
Andrew L. Lee
Publication year - 2009
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/67s3-yv45
Subject(s) - dihydrofolate reductase , antifolate , dynamics (music) , drug , modulation (music) , chemistry , pharmacology , methotrexate , computational biology , biochemistry , enzyme , biology , medicine , physics , antimetabolite , acoustics