Open AccessIn Silico Docking and Electrophysiological Characterization of Lacosamide Binding Sites on Collapsin Response Mediator Protein-2 Identifies a Pocket Important in Modulating Sodium Channel Slow Inactivation
Author(s) -
Yuying Wang,
Joel M. Brittain,
Brian W. Jarecki,
Ki Duk Park,
Sarah M. Wilson,
Bo Wang,
Rachel Hale,
Samy O. Meroueh,
Theodore R. Cummins,
Rajesh Khanna
Publication year - 2010
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/62sh-0a22
Subject(s) - lacosamide , sodium channel , in silico , chemistry , mediator , docking (animal) , electrophysiology , pharmacology , biophysics , biochemistry , neuroscience , biology , sodium , microbiology and biotechnology , medicine , epilepsy , nursing , organic chemistry , gene