Open AccessOptimization of 4-( N -Cycloamino)phenylquinazolines as a Novel Class of Tubulin-Polymerization Inhibitors Targeting the Colchicine Site
Author(s) -
Xiaofeng Wang,
Feifei Guan,
Emika Ohkoshi,
Wanjun Guo,
Lili Wang,
Dongqing Zhu,
Sheng-Biao Wang,
Liting Wang,
Ernest Hamel,
Dawei Yang,
Linna Li,
Keduo Qian,
Susan L. MorrisNatschke,
Shengtao Yuan,
KuoHsiung Lee,
Linghai Xie
Publication year - 2014
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/6211-vz21
Subject(s) - colchicine , tubulin , class (philosophy) , polymerization , microtubule , chemistry , biology , microbiology and biotechnology , computer science , genetics , organic chemistry , polymer , artificial intelligence