Open AccessPIK3CA and PIK3CB Inhibition Produce Synthetic Lethality when Combined with Estrogen Deprivation in Estrogen Receptor-Positive Breast Cancer
Author(s) -
Robert J. Crowder,
Chanpheng Phommaly,
Yu Tao,
Jeremy Hoog,
Jingqin Luo,
Charles M. Perou,
Joel S. Parker,
Mary Lou Miller,
David G. Huntsman,
Lin Li,
Jacqueline Snider,
Sherri R. Davies,
John A. Olson,
Mark A. Watson,
Anthony J. Saporita,
Jason D. Weber,
Matthew J. Ellis
Publication year - 2009
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/4zyc-tt61
Subject(s) - synthetic lethality , estrogen , breast cancer , estrogen receptor , lethality , cancer research , cancer , medicine , chemistry , biology , biochemistry , gene , toxicology , dna repair