Open AccessDiscovery of a 2,4-Diamino-7-aminoalkoxyquinazoline as a Potent and Selective Inhibitor of Histone Lysine Methyltransferase G9a
Author(s) -
Feng Liu,
Xin Chen,
Abdellah Allali-Hassani,
Amy Quinn,
Gregory A. Wasney,
Aiping Dong,
Dalia Barsyte,
I. Kozieradzki,
Guillermo Senisterra,
Irene Chau,
Alena Siarheyeva,
Dmitri Kireev,
Ajit Jadhav,
J. Martin Herold,
Stephen V. Frye,
C.H. Arrowsmith,
P. J. Brown,
Anton Simeonov,
Masoud Vedadi,
Jian Jin
Publication year - 2009
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/4yy7-c759
Subject(s) - lysine , histone methyltransferase , methyltransferase , chemistry , histone , histone h3 , biochemistry , computational biology , biology , methylation , dna , amino acid