Open AccessGlanzmann thrombasthenia resulting from a single amino acid substitution between the second and third calcium-binding domains of GPIIb. Role of the GPIIb amino terminus in integrin subunit association.
Author(s) -
D A Wilcox,
C M Paddock,
S Lyman,
J C Gill,
P J Newman
Publication year - 1995
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/16at-d993
Subject(s) - thrombasthenia , chemistry , amino acid substitution , protein subunit , calcium , amino acid , platelet , glanzmann's thrombasthenia , biochemistry , platelet membrane glycoprotein , integrin , binding site , glycoprotein , biophysics , stereochemistry , platelet aggregation , medicine , biology , receptor , organic chemistry , mutation , gene