Open AccessAsymmetric Synthesis of α-Keto Esters via Cu(II)-Catalyzed Aerobic Deacylation of Acetoacetate Alkylation Products: An Unusually Simple Synthetic Equivalent to the Glyoxylate Anion Synthon
Author(s) -
Kimberly M. Steward,
Jeffrey S. Johnson
Publication year - 2011
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/10f3-6p77
Subject(s) - synthon , glyoxylate cycle , alkylation , chemistry , catalysis , organic chemistry , ethyl acetoacetate , medicinal chemistry , enzyme