TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confers rapamycin sensitivity
Author(s) -
Mengrui Liang,
Jinhang Ma,
L. Chen,
P. Kozlowski,
W. Qin,
Defen Li,
J. Goto,
T. Shimamura,
D. N. Hayes,
M. Meyerson,
D J Kwiatkowski,
K. K. Wong
Publication year - 2010
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/0a4r-ss76
Subject(s) - kras , tsc1 , cancer research , sensitivity (control systems) , lung cancer , cancer , lung , chemistry , medicine , biology , oncology , microbiology and biotechnology , pi3k/akt/mtor pathway , signal transduction , colorectal cancer , engineering , electronic engineering
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