Autologous Whole Blood Injection For COVID-19 Can Reduce Cytokine Storm and Severity of Illness | Zendy

M Christopher | Zendy; C. Jerriton Brewin | Zendy; Ramesh Babu | Zendy; M. Mohamed Arafath | Zendy; J. Auspas | Zendy; S R Tiruvalavan | Zendy

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Autologous Whole Blood Injection For COVID-19 Can Reduce Cytokine Storm and Severity of Illness

Author(s) -

M Christopher,

C. Jerriton Brewin,

Ramesh Babu,

M. Mohamed Arafath,

J. Auspas,

S R Tiruvalavan

Publication year - 2021

Publication title -

international journal of medical research and review

Language(s) - English

Resource type - Journals

eISSN - 2321-127X

pISSN - 2320-8686

DOI - 10.17511/ijmrr.2021.i03.02

Subject(s) - medicine , autologous blood , cytokine storm , covid-19 , adjuvant , randomized controlled trial , immune system , cytokine , whole blood , surgery , anesthesia , disease , immunology , infectious disease (medical specialty)

Autologous whole blood injection is used for various indications. It has an immunomodulatory actionon the immune system. A randomized controlled two-arm study was conducted to determine IL-6levels, CT changes and mortality among adult COVID-19 patients. The trial included 30 patientsdivided into two groups. The interventional group received 2 doses of 2.5 ml of autologous wholeblood injection spaced 2 days apart. There was a statistically significant reduction in IL-6 levels onday 6 in the group receiving treatment. CT score improved in patients who received treatment. Nocases of mortality were reported in the treatment group. Autologous whole blood injection can beused as a simple, low-cost adjuvant in the treatment of adult COVID-19 patients, regardless ofdisease severity.

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