Open AccessSerum ferritin, serum LDH and d-dimer in correlation with the outcome in Covid-19.
Author(s) -
Jai Kishan,
Karthikeya Byalya,
V. Sharvan Kumar
Publication year - 2021
Publication title -
international journal of medical research and review
Language(s) - English
Resource type - Journals
eISSN - 2321-127X
pISSN - 2320-8686
DOI - 10.17511/ijmrr.2021.i01.07
Subject(s) - medicine , discontinuation , medroxyprogesterone acetate , adverse effect , progestin , side effect (computer science) , ferritin , gastroenterology , physiology , obstetrics , estrogen , computer science , programming language
BACKGROUND: Early detection of comorbidities, severe patients with SARS-COV-2 and helpfuldiagnostic tools is very important for individual treatment and helps us in assessing the outcome ofmoderate to severe patients. METHOD: In our study we have included 108 patients with RT-PCRpositive for SARS COV-2 and the samples for D-dimer, Sr. LDH and Sr.ferritin were sent andanalyzed. RESULTS: the effect of D-dimer, serum LDH and serum ferritin individually andcombinedly showed in our study there was no significant difference between D-dimer and theoutcome however there was a significant p-value of <0.001 with serum LDH and the outcome, andp-value of 0.016 with serum ferritin and outcome. CONCLUSIONS: When the markers individuallyanalyzed they showed a significant association between outcome and markers, in elevated O2andnormal patients. Mean D dimer, serum ferritin and serum LDH were high among subjects whorequired NIV and low among subjects who required O2, on Room air and intubated respectively. Inhospitalized patients with respiratory distress, we recommend clinicians closely monitor serumferritin, serum LDH and D-dimer and also other markers of severity, WBC count, lymphocyte count,platelet count, IL-6 as markers for potential progression to critical illness, has been under the study,however our study sample being 108, a study with a larger number of samples required to predictthe outcome.