Open AccessRespiratory adverse events associated with deep propofol sedation during upper gastrointestinal procedures in children
Author(s) -
Novotny William E,
Nguyen Mihn Khanh,
Jose Folashade,
Haislip Dynita,
Grothmann Gregg A,
Dmitry Tumin
Publication year - 2021
Publication title -
global journal of anesthesiology
Language(s) - English
Resource type - Journals
ISSN - 2455-3476
DOI - 10.17352/2455-3476.000053
Subject(s) - medicine , propofol , sedation , airway , anesthesia , adverse effect , glottis , respiratory system , airway obstruction , positive airway pressure , surgery , larynx , obstructive sleep apnea
Background/Aims: Upper airway stimulation with endoscopes and pH-impedance probes during deep propofol sedation confers unknown risk for associated respiratory adverse airway events. This report quantifies frequencies of such events and airway rescue interventions associated with Esophagogastroduodenoscopies (EGD) and multi-channel intraluminal acid detection impedance probe (MIIP) placements. Methods: This was a prospective observational study regarding occurrence of adverse respiratory events in 42 children undergoing propofol sedated EGDs and MIIP placements: Group 1. (n=21 EGDs), Group2 (n=21 EGDs before MIIP), Group 3. (n=21 during MIIP). Results: All procedures were successfully completed using deep propofol sedation. Respiratory events were transient and associated with no morbidity or mortality. Nearly half of each group experienced a respiratory event. “Partial airway obstruction” during 42 EGDs occurred in 28.6% and responded to simple airway interventions. “Complete airway obstruction” occurred during 1/42 EGDs and 2/21 MIIPs. Throughout MIIP placement, endoscopic visualization of the glottis was maintained and unnecessary stimulation of the glottis was avoided; nonetheless, complete airway obstruction occurred in 2/21. Advanced airway rescue maneuvers were not required in either instance. Conclusions: Respiratory adverse events commonly occurred during EGDs and MIIP placements. All events were successfully rescued by simple airway interventions.