Open AccessMedicinal Plants Extracts Impact on Oxidative Stress in Mice Brain under the Physiological Conditions: the Effects of Corn Silk, Parsley, and Bearberry
Author(s) -
Marijana Vranješ,
Dubravka Štajner,
Dejan Vranješ,
Bojana Blagojević,
Ksenija Pavlović,
Dubravka Milanov,
Boris M. Popović
Publication year - 2021
Publication title -
acta chimica slovenica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.289
H-Index - 46
eISSN - 1580-3155
pISSN - 1318-0207
DOI - 10.17344/acsi.2021.6885
Subject(s) - antioxidant , oxidative stress , lipid peroxidation , catalase , silk , glutathione , chemistry , brain tissue , food science , biology , biochemistry , traditional medicine , enzyme , medicine , computer science , anatomy , operating system
This study was performed to examine the effects of medicinal plant extracts of corn silk (Stigma maydis), parsley leaf (Petroselini folium), and bearberry leaf (Uvae ursi folium) on antioxidant status of the brain of experimental animals (mice) under the physiological conditions. Biological properties of these plants are insufficiently investigated and the aim was to explore their possible antioxidant effects that can alleviate oxidative damage of the brain tissue. Corn silk extract showed positive effect on activities of antioxidant enzymes in mice brain tissue. Parsley extract induced the increase in glutathione content and decrease of lipid peroxidation. Bearberry leaf extract induced catalase activity and decrease of hydroxyl radical content, while malonyldialdehide accumulation was maintained at the control level. Results obtained in this study support the use of corn silk, parsley and bearberry leaves as natural antioxidant sources in the prevention and treatment of brain tissue damages and different diseases caused by oxidative stress.