Open AccessSynthesis, Characterization and Crystal Structures of Zinc(II) and Cobalt(III) Complexes Derived from Tridentate NNO- and NON- Schiff Bases with Antibacterial Activities
Author(s) -
Heng-Yu Qian
Publication year - 2021
Publication title -
acta chimica slovenica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.289
H-Index - 46
eISSN - 1580-3155
pISSN - 1318-0207
DOI - 10.17344/acsi.2021.6721
Subject(s) - molar conductivity , chemistry , octahedron , square pyramidal molecular geometry , trigonal bipyramidal molecular geometry , zinc , hydrogen bond , bipyramid , cobalt , schiff base , crystallography , crystal structure , molecule , stereochemistry , medicinal chemistry , inorganic chemistry , elemental analysis , organic chemistry
Two new polynuclear zinc complexes [Zn2Br2(L1)2] (1) and [Zn(μ1,5-dca)L2]n (2), and two new mononuclear cobalt(III) complexes [CoL1N3(Brsal)] (3) and [CoL2(HL2)] (4), where L1 = 5-bromo-2-(((2-dimethylamino)ethyl)imino)methyl)phenolate, L2 = 5-bromo-2-(((2-hydroxyethyl)imino)methyl)phenolate, dca = dicyanoamide, Brsal = 5-bromo-2-formylphenolate, have been synthesized and characterized. The complexes were characterized by elemental analyses, IR, UVVis spectra, molar conductivity, and single crystal X-ray diffraction. X-ray analysis indicates that the Zn atoms in complex 1 are in distorted square pyramidal coordination, the Zn atoms in complex 2 are in distorted trigonal bipyramidal coordination, and the Co atoms in complexes 3 and 4 are in octahedral coordination. The molecules of the complexes are stacked through π···π interactions and hydrogen bonds. The complexes were assayed for antibacterial activities against three Gram-positive bacterial strains (B. subtilis, S. aureus, and St. faecalis) and three Gram-negative bacterial strains (E. coli, P. aeruginosa, and E. cloacae) by MTT method.