Open AccessSynthesis, structures, and antimicrobial activities of two cobalt(II) complexes [Co(L1)2(OH2)2] and [Co(L2)2]
Author(s) -
YaPing Han,
Li Wang,
Qingbin Li,
Ling-Wei Xue
Publication year - 2017
Publication title -
acta chimica slovenica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.289
H-Index - 46
eISSN - 1580-3155
pISSN - 1318-0207
DOI - 10.17344/acsi.2016.3019
Subject(s) - cobalt , chemistry , deprotonation , ligand (biochemistry) , octahedron , schiff base , crystallography , methanol , octahedral molecular geometry , crystal structure , stereochemistry , medicinal chemistry , inorganic chemistry , organic chemistry , ion , biochemistry , receptor
A new cobalt(II) complex, [Co(L1)2(OH2)2] (1), was prepared by the reaction of 3-bromo-5-chlorosalicylaldehyde (HL1) with cobalt nitrate in methanol. Reaction of 1 with cyclopropylamine in methanol afforded the Schiff base cobalt(II) complex, [Co(L2)2] (2), where L2 is the deprotonated form of 2-bromo-4-chloro-6-(cyclopropyliminomethyl)phenol (HL2). The complexes have been characterized by elemental analyses, IR spectroscopy, and single-crystal X-ray diffraction. The L1 ligand coordinates to the Co atom through the phenolate O and carbonyl O atoms, while the L2 ligand coordinates to the Co atom through the phenolate O and imino N atoms. The Co atom in complex 1 adopts octahedral coordination and that in complex 2 adopts tetrahedral coordination. The effect of the free ligands and the cobalt complexes on the antimicrobial activities against Staphylococcus aureus, Escherichia coli, and Candida albicans was studied.