Voltammetric Assay of Metformin Hydrochloride Using Pyrogallol Modified Carbon Paste Electrode | Zendy

Ali K. Attia | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Voltammetric Assay of Metformin Hydrochloride Using Pyrogallol Modified Carbon Paste Electrode

Author(s) -

Ali K. Attia

Publication year - 2015

Publication title -

acta chimica slovenica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.289

H-Index - 46

eISSN - 1580-3155

pISSN - 1318-0207

DOI - 10.17344/acsi.2014.950

Subject(s) - pyrogallol , detection limit , chemistry , differential pulse voltammetry , carbon paste electrode , hydrochloride , cyclic voltammetry , voltammetry , electrode , nuclear chemistry , metformin hydrochloride , chromatography , electrochemistry , inorganic chemistry , metformin , organic chemistry , medicine , diabetes mellitus , endocrinology

The electrooxidative behavior and determination of metformin hydrochloride, anti-hyperglycemic drug, on a pyrogallol modified carbon paste electrode were investigated using cyclic voltammetry and differential pulse voltammetry. Metformin hydrochloride shows an irreversible oxidation behavior over a wide interval of pH (Britton-Robinson buffers, pH 2-9). The peak current varied linearly in the range comprised between 8.0 × 10(-7) and 6.0 × 10(-6) mol/L with detection limit of 6.63 × 10(-8) mol/L and limit of quantification of 2.21 × 10(-7) mol/L. The method was proposed for the determination of metformin hydrochloride in dosage forms and urine.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research