Open AccessPredictive performance of CT for adverse outcomes among COVID-19 suspected patients: a two-center retrospective study
Author(s) -
Begümhan Baysal,
Mahmut Bilal Doğan,
Mutlu Gülbay,
Mine Sorkun,
Murathan Köksal,
Aliye Baştuğ,
Sümeyye Kazancıoğlu,
Bahadır Orkun Özbay,
Sacit İçten,
Ferhat Arslan,
Yasemin Çağ,
Hürrem Bodur,
Haluk Vahaboğlu
Publication year - 2021
Publication title -
bosnian journal of basic medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 25
eISSN - 1840-4812
pISSN - 1512-8601
DOI - 10.17305/bjbms.2020.5466
Subject(s) - medicine , receiver operating characteristic , retrospective cohort study , pneumonia , covid-19 , adverse effect , area under the curve , predictive value of tests , radiological weapon , radiology , disease , infectious disease (medical specialty)
The aim of the study was to compare the performance of various computed tomography (CT) reporting tools, including zonal CT visual score (ZCVS), the number of involved lobes, and Radiological Society of North America (RSNA) categorization in predicting adverse outcomes among patients hospitalized due to the lower respiratory symptoms during the coronavirus disease 2019 (COVID-19) pandemic. A total of 405 patients admitted with severe respiratory symptoms who underwent a chest CT were enrolled. The primary adverse outcome was intensive care unit (ICU) admission of patients. Predictive performances of reporting tools were compared using the area under the receiver operating characteristic curves (AUC ROC). Among the 405 patients, 39 (9.63%) required ICU support during their hospital stay. At least two or more observers reported a typical and indeterminate COVID-19 pneumonia CT pattern according to RSNA categorization in 70% (285/405) of patients. Among these, 63% (179/285) had a positive polymerase chain reaction (PCR test for the SARS-CoV-2 virus. The median number of lobes involved according to CT was higher in patients who required ICU support (median interquartile range [IQR], 5[3; 5] vs. 3[0; 5]). The median ZCVS score was higher among the patients that subsequently required ICU support (median [IQR], 4[0; 12] vs. 13[5.75; 24]). The bootstrap comparisons of AUC ROC showed significant differences between reporting tools, and the ZCVS was found to be superior (AUC ROC, 71-75%). The ZCVS score at the first admission showed a linear and significant association with adverse outcomes among patients with the lower respiratory tract symptoms during the COVID-19 pandemic.