Open AccessIntestinal histological findings in patients with spondyloarthritis: a study on the relationship with disease activity
Author(s) -
Juliana Simioni,
Thelma Larocca Skare,
Sérgio Ossamu Ioshii,
Ana Cristina Viana Campos,
B. Longo,
Iara Messias-Reason,
Renato Nisihara
Publication year - 2022
Publication title -
revista española de enfermedades digestivas/revista española de enfermedades digestivas
Language(s) - English
Resource type - Journals
eISSN - 2340-4167
pISSN - 1130-0108
DOI - 10.17235/reed.2022.8930/2022
Subject(s) - medicine , asymptomatic , subclinical infection , inflammation , inflammatory bowel disease , etiology , disease , gastroenterology , pathology
The role of intestinal microbioma and subclinical bowel inflammation in the etiology of sponsyloarthritis (SpA) has gained a lot of attention recently. Almost 65% of SpA patients will have asymptomatic bowel inflammation if assessed by ileocolonoscopy. The connection between intestinal inflammation and SpA originated the gut-joint axis hypothesis in which monocytes and T cells found in the joint would have origin in the gut.