Open AccessPrimary synchronous rectal squamous cell carcinoma and its exceptional response to chemoradiotherapy
Author(s) -
Esteban Fuentes-Valenzuela,
Begoña Becoechea Gómez,
María Miguel Lucero Salaverry,
Luis E. Abella
Publication year - 2021
Publication title -
revista española de enfermedades digestivas/revista española de enfermedades digestivas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.331
H-Index - 38
eISSN - 2340-4167
pISSN - 1130-0108
DOI - 10.17235/reed.2021.8068/2021
Subject(s) - rectum , medicine , chemoradiotherapy , lamina propria , anal canal , lesion , colonoscopy , proctoscopy , basal cell , radiology , colorectal cancer , gastroenterology , pathology , radiation therapy , epithelium , cancer
We present the case of a 51-year-old female with a 2-month history of intense anal pain and rectal bleeding. A digital rectal exam revealed a possible lower rectal mass. A colonoscopy was then performed that showed a 5 x 6-cm lesion in the middle rectum and a second 3-cm lesion in the lower rectum, without affecting the anal canal. Multiple biopsies were taken and the histopathologic analysis revealed a moderately differentiated squamous-cell proliferation invading beyond the lamina propria. The CT scan confirmed a middle rectum T4N2bM0 and a lower rectum T3N0M0 synchronous neoplasia. These findings were compatible with a synchronous squamous-cell carcinoma (SCC).