Open AccessEBVMCU in a liver-transplant patient
Author(s) -
M Librero Jiménez,
Maria Dolores Espinosa Aguilar
Publication year - 2021
Publication title -
revista española de enfermedades digestivas/revista española de enfermedades digestivas
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.331
H-Index - 38
eISSN - 2340-4167
pISSN - 1130-0108
DOI - 10.17235/reed.2021.8064/2021
Subject(s) - medicine , colonoscopy , gastroenterology , immunosuppression , tacrolimus , diarrhea , liver transplantation , cytomegalovirus , anemia , surgery , virus , transplantation , immunology , colorectal cancer , viral disease , herpesviridae , cancer
A 36-year-old male was admitted to our hospital with diarrhea, weakness and loss of appetite over two months. He had received a liver transplant two years before and was taking immunosuppressors (everolimus, mycophenolate mofetil and tacrolimus). Initial laboratory tests showed iron-deficiency anemia (Hb 9.8 g/dl), lymphopenia and mild elevation in C-reactive protein (35 mg/l). Blood and stool cultures, and cytomegalovirus (CMV) quantitation in blood were all negative. Finally, the colonoscopy showed two rectal fimbriated ulcers close to the anal sphincter and multiple biopsies from the ulcer margins identified the presence of Epstein-Barr virus (EBV). All symptoms were completely resolved three weeks after immunosuppression was diminished. He underwent a follow-up colonoscopy, without any evidence of the former ulcers.