Open AccessINTESTINAL BURYING OF THE JEJUNAL-TUBE OF A PEG-J LEVODOPA-CARBIDOPA RELEASE SYSTEM FOR PARKINSON�S DISEASE. SUCCESSFUL ENDOSCOPIC MANAGEMENT.
Author(s) -
Óscar Moralejo Lozano,
Adrián Joaquín Barrajón Masa,
Michel Colmenares Bulgheroni
Publication year - 2020
Publication title -
revista española de enfermedades digestivas/revista española de enfermedades digestivas
Language(s) - English
Resource type - Journals
eISSN - 2340-4167
pISSN - 1130-0108
DOI - 10.17235/reed.2020.7180/2020
Subject(s) - medicine , carbidopa , parkinson's disease , levodopa , peg ratio , immediate release , gastroenterology , feeding tube , disease , pharmacology , surgery , finance , economics
Levodopa-carbidopa intestinal gel (LCIG) continuous infusion into the jejunum through a percutaneous endoscopic gastrostomy with a jejunal extension (PEG-J) is an alternative therapy for Parkinson's disease (PD) patients, with a very poor control of their symptoms on regular oral medications (Hoehn-Yahr stage IV). Around 62.2 % of patients present procedure and device-related adverse effects (AE), with an 8.2 % rate of mayor complications.