Open AccessAssociation between ustekinumab trough concentrations and biochemical outcomes in patients with Crohn�s disease. A real life study
Author(s) -
Rosa Gómez Espín,
Isabel Nicolás de Prado,
M Gil Candel,
Marta González Carrión,
Lorena Rentero Redondo,
Carles Iniesta Navalón
Publication year - 2020
Publication title -
revista española de enfermedades digestivas/revista española de enfermedades digestivas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.331
H-Index - 38
eISSN - 2340-4167
pISSN - 1130-0108
DOI - 10.17235/reed.2020.7124/2020
Subject(s) - ustekinumab , medicine , crohn's disease , disease , crohn disease , gastroenterology , adalimumab
numerous studies have shown a positive correlation between serum biologic drug concentrations and favorable therapeutic outcomes during the induction and maintenance period in patients with Crohn's disease (CD). To our knowledge, only a few and contradictory studies have determined the association between ustekinumab (UST) trough concentrations and biological outcomes. This study aimed to investigate the relationship between ustekinumab trough concentrations and biological outcomes in a real-world setting.