Open AccessPrognostic differences between lymphoepithelioma-like colon carcinoma and colon adenocarcinoma
Author(s) -
Irma Romero,
Cristina González Puga,
Pedro García Saura
Publication year - 2018
Publication title -
revista española de enfermedades digestivas/revista española de enfermedades digestivas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.331
H-Index - 38
eISSN - 2340-4167
pISSN - 1130-0108
DOI - 10.17235/reed.2018.5765/2018
Subject(s) - microsatellite instability , medicine , lymphoepithelioma like carcinoma , adenocarcinoma , pathogenesis , infiltration (hvac) , pathology , epstein–barr virus , colorectal cancer , colon adenocarcinoma , colon carcinoma , virus , colonic carcinoma , lymphoepithelioma , carcinoma , cancer research , oncology , microsatellite , immunology , cancer , biology , gene , biochemistry , allele , thermodynamics , physics
Lymphoepithelioma-like colon carcinoma (LELC) is rare. The Epstein-Barr virus (EBV) hasn´t been implicated in the pathogenesis of LELC of the colon, but they may in fact be more strongly associated with MSI. Its treatment is identical to adenocarcinoma. However, lymphocyte infiltration and microsatellite instability have been associated with better prognosis.