Open AccessUtility of neoadjuvant therapy in rectal GIST
Author(s) -
Víctor López-López,
José Antonio López Fernández,
Pascual Parrilla
Publication year - 2017
Publication title -
revista española de enfermedades digestivas/revista española de enfermedades digestivas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.331
H-Index - 38
eISSN - 2340-4167
pISSN - 1130-0108
DOI - 10.17235/reed.2017.4751/2016
Subject(s) - medicine , gist , neoadjuvant therapy , resection , imatinib , surgical resection , surgery , general surgery , cancer , stromal cell , breast cancer , myeloid leukemia
Neoadjuvant therapy with Imatinib is the preferred treatment for rectal GISTs in order to reduce the aggressiveness of a surgical resection. At present, surgical resection does not require wide surgical margins. There is also a lot of controversy with regard to the need for a broad anatomical resection or if a local resection is sufficient and maintains maximum oncological safety and minimum morbidity and mortality. We present a case report of a rectal GIST with a good response to neoadjuvant treatment which allowed a transanal resection.