Open AccessPaclitaxel inhibits proliferation and invasion and promotes apoptosis of breast cancer cells by blocking activation of the PI3K/AKT signaling pathway
Author(s) -
Gang Li,
Dongxin Xu,
Jinju Sun,
Sen Zhao,
Dan Zheng
Publication year - 2020
Publication title -
advances in clinical and experimental medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.486
H-Index - 27
eISSN - 2451-2680
pISSN - 1899-5276
DOI - 10.17219/acem/127681
Subject(s) - pi3k/akt/mtor pathway , protein kinase b , apoptosis , viability assay , cell growth , cancer research , vascular endothelial growth factor , cell cycle , mtt assay , paclitaxel , microbiology and biotechnology , chemistry , biology , medicine , cancer , biochemistry , vegf receptors
Breast cancer has the highest incidence and mortality among all cancers in women. Paclitaxel (PTX) has a notable therapeutic effect on cancer in clinical practice.