Paclitaxel inhibits proliferation and invasion and promotes apoptosis of breast cancer cells by blocking activation of the PI3K/AKT signaling pathway | Zendy

Gang Li | Zendy; Dongxin Xu | Zendy; Jinju Sun | Zendy; Shiyun Zhao | Zendy; Dan Zheng | Zendy

Open Access

Paclitaxel inhibits proliferation and invasion and promotes apoptosis of breast cancer cells by blocking activation of the PI3K/AKT signaling pathway

Author(s) -

Gang Li,

Dongxin Xu,

Jinju Sun,

Shiyun Zhao,

Dan Zheng

Publication year - 2020

Publication title -

advances in clinical and experimental medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.486

H-Index - 27

eISSN - 2451-2680

pISSN - 1899-5276

DOI - 10.17219/acem/127681

Subject(s) - pi3k/akt/mtor pathway , protein kinase b , apoptosis , viability assay , cell growth , cancer research , vascular endothelial growth factor , cell cycle , mtt assay , paclitaxel , microbiology and biotechnology , chemistry , biology , medicine , cancer , biochemistry , vegf receptors

Breast cancer has the highest incidence and mortality among all cancers in women. Paclitaxel (PTX) has a notable therapeutic effect on cancer in clinical practice.

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