Open AccessMicroRNA-548k upregulates a spliced variant of human CD2-associated protein by targeting its promoter
Author(s) -
Nannan Li,
Guoping Zhou
Publication year - 2020
Publication title -
advances in clinical and experimental medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.486
H-Index - 27
eISSN - 2451-2680
pISSN - 1899-5276
DOI - 10.17219/acem/122168
Subject(s) - chromatin immunoprecipitation , promoter , microbiology and biotechnology , hek 293 cells , luciferase , messenger rna , microrna , biology , gene expression , transcription (linguistics) , immunoprecipitation , rna polymerase ii , chromatin , gene , regulation of gene expression , transcription factor , transfection , genetics , linguistics , philosophy
MicroRNAs (miRNAa) regulate gene expression by repressing the translation or directing the degradation of mRNA in the cytoplasm. However, recent studies have shown that miRNAs act to regulate transcription at target gene promoters.