Open AccessRelations between circulating and myocardial fibrosis-linked microRNAs with left ventricular reverse remodeling in dilated cardiomyopathy
Author(s) -
Ewa Dziewięcka,
Justyna TotońŻurańska,
Paweł Wołkow,
Maria Kołton-Wróż,
Ewelina Pitera,
Sylwia WiśniowskaŚmiałek,
Lusine Khachatryan,
Aleksandra Karabinowska,
Maria Szymonowicz,
Piotr Podolec,
Paweł Rubiś
Publication year - 2020
Publication title -
advances in clinical and experimental medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.486
H-Index - 27
eISSN - 2451-2680
pISSN - 1899-5276
DOI - 10.17219/acem/115088
Subject(s) - medicine , ejection fraction , dilated cardiomyopathy , cardiology , myocardial fibrosis , ventricle , ventricular remodeling , fibrosis , heart failure
Left ventricular reverse remodeling (LVRR) determines clinical status and outcomes in dilated cardiomyopathy (DCM). The extent of myocardial fibrosis is connected to the systolic function of the heart. The recent discovery of the contribution of microRNAs (miRs) to the regulation of cardiac remodeling, LVRR and fibrosis warrants exploration.