Open AccessReproductive potential of male rats in the experimental model of wildfire
Author(s) -
Vera A. Vokina,
AUTHOR_ID,
Е. А. Капустина,
М. А. Новиков,
Elizaveta S. Andreeva,
AUTHOR_ID,
AUTHOR_ID,
AUTHOR_ID
Publication year - 2021
Publication title -
vestnik permskogo universiteta. seriâ biologiâ
Language(s) - English
Resource type - Journals
ISSN - 1994-9952
DOI - 10.17072/1994-9952-2021-1-70-76
Subject(s) - spermatogenesis , dna fragmentation , biology , andrology , methylation , physiology , dna methylation , male reproductive system , medicine , endocrinology , sperm , dna , genetics , gene , gene expression , apoptosis , programmed cell death
The assessment of the indicators of the reproductive potential of male white rats exposed to smoke for 1 month was carried out. Examination of exposed animals included determination of the spermatogenesis index and the level of DNA fragmentation and methylation in the testes and blood. A statistically signifi-cant increase in the level of genome-wide methylation in the blood of rats exposed to smoke was revealed. A morphometric study of the testis tissue revealed a violation of spermatogenesis indices in exposed rats.