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A case series of super‐refractory status epilepticus successfully treated with electroconvulsive therapy
Author(s) -
Tan Hui Jan,
Tee Tze Yuan,
Husin Mazlina,
Khoo Ching Soong,
Woon Luke SyCherng
Publication year - 2020
Publication title -
epileptic disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.673
H-Index - 53
eISSN - 1950-6945
pISSN - 1294-9361
DOI - 10.1684/epd.2020.1233
Subject(s) - status epilepticus , medicine , electroconvulsive therapy , refractory (planetary science) , ketogenic diet , neurointensive care , anesthesia , hypothermia , epilepsy , pediatrics , psychiatry , physics , electroconvulsive shock , astrobiology
Super‐refractory status epilepticus (SRSE) is a neurocritical emergency, associated with significant morbidity and mortality. The precise pathophysiology is still not completely understood. The likelihood of spontaneous seizure termination reduces with time, and it is of paramount importance to abort status in order to prevent permanent long‐term neurological sequelae and death. A few neuroprotective strategies, such as general anaesthesia, steroids, ketogenic diet and hypothermia, have been used to treat SRSE, however, the clinical outcome remains inconclusive. We herein present two cases of SRSE, which were successfully treated with electroconvulsive therapy (ECT) after failing all pharmacological measures.