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Brain connectivity changes during ictal coughing
Author(s) -
Roux Alexandra,
Lagarde Stanislas,
McGonigal Aileen,
Bartolomei Fabrice
Publication year - 2019
Publication title -
epileptic disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.673
H-Index - 53
eISSN - 1950-6945
pISSN - 1294-9361
DOI - 10.1684/epd.2019.1084
Subject(s) - ictal , neuroscience , psychology , medicine , epilepsy , anesthesia
Coughing is a reflex phenomenon that is protective for the upper airways, involving both a reflex arc in the brainstem and cortical control. Ictal coughing has been prominently reported in temporal lobe seizures, but precise anatomo‐electrical correlations are lacking. We report a patient who presented with persistent coughing at seizure onset. We studied intracerebrally recorded seizures (using stereo‐electroencephalography) in order to describe the anatomo‐functional correlations associated with this sign. Coughing followed seizure onset in the medial temporal lobe. A functional connectivity study (h 2 estimation of interdependencies) showed that during coughing, a network of cortical and subcortical regions was involved, particularly the perisylvian cortices and the caudate nucleus.