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Exceptional response to brivaracetam in a patient with refractory idiopathic generalized epilepsy and absence seizures
Author(s) -
GrandeMartín Alberto,
SopelanaGaray David,
PardalFernández José Manuel,
SánchezHonrubia Rosa María,
SánchezLarsen Álvaro Abelardo
Publication year - 2018
Publication title -
epileptic disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.673
H-Index - 53
eISSN - 1950-6945
pISSN - 1294-9361
DOI - 10.1684/epd.2017.0939
Subject(s) - levetiracetam , epilepsy , idiopathic generalized epilepsy , refractory (planetary science) , generalized epilepsy , medicine , antiepileptic drug , adjunctive treatment , pediatrics , psychiatry , physics , astrobiology
Brivaracetam is currently indicated as adjunctive therapy for patients with focal‐onset seizures with or without secondary generalization. However, it has been suggested that it could provide broad‐spectrum efficacy given its similarity to levetiracetam and based on the results from preclinical studies and others of patients with generalized epilepsy. We present the case of a woman with refractory idiopathic generalized epilepsy and absence seizures with dramatic response to brivaracetam. Our report supports a consideration of treatment with this new antiepileptic drug on a case‐by‐case basis in patients with refractory generalized epilepsy, while we await further studies on this topic.