Multifocal dysembryoplastic neuroepithelial tumours associated with refractory epilepsy | Zendy

Yang Andrew I. | Zendy; Khawaja Ayaz M. | Zendy; BallesterFuentes Leo | Zendy; Pack Svetlana D. | Zendy; Abdullaev Ziedulla | Zendy; Patronas Nicholas J. | Zendy; Inati Sara K. | Zendy; Theodore William H. | Zendy; Quezado Martha M. | Zendy; Zaghloul Kareem A. | Zendy

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Multifocal dysembryoplastic neuroepithelial tumours associated with refractory epilepsy

Author(s) -

Yang Andrew I.,

Khawaja Ayaz M.,

BallesterFuentes Leo,

Pack Svetlana D.,

Abdullaev Ziedulla,

Patronas Nicholas J.,

Inati Sara K.,

Theodore William H.,

Quezado Martha M.,

Zaghloul Kareem A.

Publication year - 2014

Publication title -

epileptic disorders

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.673

H-Index - 53

eISSN - 1950-6945

pISSN - 1294-9361

DOI - 10.1684/epd.2014.0680

Subject(s) - epilepsy , refractory (planetary science) , neuroepithelial cell , medicine , pathology , biology , genetics , stem cell , neural stem cell , psychiatry , astrobiology

Dysembryoplastic neuroepithelial tumours (DNET) are a common cause of tumour‐associated epilepsy, and are usually located in the temporal lobes. We present a case of multifocal DNETs in both infra‐ and supra‐tentorial locations, in a 23‐year‐old man with a coincident Type I Chiari malformation, presenting with medically refractory focal seizures. The extensive anatomical distribution of the lesions suggests a genetic component in their tumourigenesis.

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