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Multifocal dysembryoplastic neuroepithelial tumours associated with refractory epilepsy
Author(s) -
Yang Andrew I.,
Khawaja Ayaz M.,
BallesterFuentes Leo,
Pack Svetlana D.,
Abdullaev Ziedulla,
Patronas Nicholas J.,
Inati Sara K.,
Theodore William H.,
Quezado Martha M.,
Zaghloul Kareem A.
Publication year - 2014
Publication title -
epileptic disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.673
H-Index - 53
eISSN - 1950-6945
pISSN - 1294-9361
DOI - 10.1684/epd.2014.0680
Subject(s) - epilepsy , refractory (planetary science) , neuroepithelial cell , medicine , pathology , biology , genetics , stem cell , neural stem cell , psychiatry , astrobiology
Dysembryoplastic neuroepithelial tumours (DNET) are a common cause of tumour‐associated epilepsy, and are usually located in the temporal lobes. We present a case of multifocal DNETs in both infra‐ and supra‐tentorial locations, in a 23‐year‐old man with a coincident Type I Chiari malformation, presenting with medically refractory focal seizures. The extensive anatomical distribution of the lesions suggests a genetic component in their tumourigenesis.