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Continuous spikes and waves during slow sleep in a child with karyotype 47, XYY
Author(s) -
Cianci Vittoria,
Ferlazzo Edoardo,
De Martino Giuseppe,
Vinci Angela,
Gasparini Sara,
Tripodi Giovanbattista Gaspare,
Aguglia Umberto
Publication year - 2014
Publication title -
epileptic disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.673
H-Index - 53
eISSN - 1950-6945
pISSN - 1294-9361
DOI - 10.1684/epd.2014.0651
Subject(s) - karyotype , epilepsy , electroencephalography , trisomy , aneuploidy , audiology , medicine , psychology , chromosome , pediatrics , biology , neuroscience , genetics , gene
The XYY syndrome is a sex chromosome aneuploidy occurring in one of 1,000 live male births. Only few data exist regarding the correlation between this syndrome and epilepsy. An EEG pattern suggestive of benign focal epilepsy with centro‐temporal spikes has recently been described in four XYY patients. We report the first patient with XYY trisomy, rolandic spikes, and atypical evolution with continuous spikes and waves during slow sleep (CSWSS). The present report suggests that the association between an EEG pattern similar to that of BECTS and 47, XYY karyotype may not be coincidental. Moreover, we show that an atypical evolution with CSWSS may occur in this chromosomal disorder.