Open AccessRetrospective analysis of the performance of the SARS-CoV-2 rapid antigen detection test compared to the reference RT-PCR test
Author(s) -
Mathieu Bernard,
Gina Cosentino,
Laura Pieri,
Pierre Zachary,
Michael D. Buser,
Laurent Kbaier,
Jean-Marc Giannoli
Publication year - 2021
Publication title -
annales de biologie clinique
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.167
H-Index - 27
eISSN - 1950-6112
pISSN - 0003-3898
DOI - 10.1684/abc.2021.1641
Subject(s) - test (biology) , covid-19 , medicine , virology , antigen , immunology , biology , paleontology , disease , infectious disease (medical specialty)
Discovered in 2019 in the region of Wuhan, China, the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) rapidly established itself as a major pathogenic agent of morbidity and mortality. France has implemented a strategy to fight this virus which relies essentially on widespread RT-PCR virological testing in order to isolate positive patients. Antigenic tests have recently been made available to help the diagnostics. We have conducted a retrospective study to determine the sensitivity of these antigenic tests, comparing them to the reference RT-PCR method.