Retrospective analysis of the performance of the SARS-CoV-2 rapid antigen detection test compared to the reference RT-PCR test | Zendy

Mathieu Bernard | Zendy; Gina Cosentino | Zendy; Laura Pieri | Zendy; Pierre Zachary | Zendy; Michael Buser | Zendy; Laurent Kbaier | Zendy; Jean-Marc Giannoli | Zendy

Open Access

Retrospective analysis of the performance of the SARS-CoV-2 rapid antigen detection test compared to the reference RT-PCR test

Author(s) -

Mathieu Bernard,

Gina Cosentino,

Laura Pieri,

Pierre Zachary,

Michael Buser,

Laurent Kbaier,

Jean-Marc Giannoli

Publication year - 2021

Publication title -

annales de biologie clinique

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.167

H-Index - 27

eISSN - 1950-6112

pISSN - 0003-3898

DOI - 10.1684/abc.2021.1641

Subject(s) - asymptomatic , covid-19 , test (biology) , medicine , false negative reactions , retrospective cohort study , diagnostic test , viral load , pcr test , virology , immunology , emergency medicine , polymerase chain reaction , biology , virus , genetics , paleontology , disease , outbreak , gene , infectious disease (medical specialty)

Discovered in 2019 in the region of Wuhan, China, the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) rapidly established itself as a major pathogenic agent of morbidity and mortality. France has implemented a strategy to fight this virus which relies essentially on widespread RT-PCR virological testing in order to isolate positive patients. Antigenic tests have recently been made available to help the diagnostics. We have conducted a retrospective study to determine the sensitivity of these antigenic tests, comparing them to the reference RT-PCR method.

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