Open AccessHaemodialysis Tunisian patient with acquired factor V inhibitor associated to arteriovenous shunt thrombosis
Author(s) -
Ikbel Ghachem,
Wijdène El Borgi,
Sarra Fekih Salem,
Fatma Ben Lakhal,
Amel Chelbi,
Iheb Ghiriani,
Emna Gouider
Publication year - 2020
Publication title -
annales de biologie clinique
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.167
H-Index - 27
eISSN - 1950-6112
pISSN - 0003-3898
DOI - 10.1684/abc.2020.1540
Subject(s) - medicine , autoantibody , shunt (medical) , thrombosis , hemodialysis , immunology , antibody
Factor V deficiency is a rare hemostatic disorder. It may present with a diverse spectrum of symptoms due to a variety of mechanisms including development of autoantibodies associated with a number of conditions. We report a first case of factor V deficiency in Tunisian hemodialysis patient due to an autoantibody most likely secondary to antibiotic exposure responsible for an arteriovenous shunt thrombosis rather than bleeding. We discuss here the clinical and biological features of acquired factor V inhibitor and provide a short review of the current literature.