B-cell non-Hodgkin lymphoma discovery after observation of a platelet satellitism around atypical lymphocytes | Zendy

Anne Gatignol | Zendy; Marie Amirault | Zendy; Éric Legac | Zendy; Julien Decker | Zendy

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B-cell non-Hodgkin lymphoma discovery after observation of a platelet satellitism around atypical lymphocytes

Author(s) -

Anne Gatignol,

Marie Amirault,

Éric Legac,

Julien Decker

Publication year - 2019

Publication title -

annales de biologie clinique

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.167

H-Index - 27

eISSN - 1950-6112

pISSN - 0003-3898

DOI - 10.1684/abc.2018.1406

Subject(s) - gynecology , microbiology and biotechnology , cd5 , population , medicine , lymphoma , biology , immunology , environmental health

We report the case of an 83-year-old woman admitted to the accident and emergency unit for pneumopathy. The blood cell count on the DXH automaton (Coulter® ™ UniCel® DxH) found a normochromic and normocytic anemia, anormal platelet count and subnormal leukocyte formula. The only alarm raised by the automaton was the presence of a basocytosis. A control of the leucocyte count by flow cytometry and blood smear has been done. It revealed there was no basocytosis, but showed the presence of an atypical monomorphic lymphocytes B population (T/B < 1 ratio in flow cytometry), around which platelets aggregated. The lymphocytic immunophenotyping allowed us to highlight the presence of a CD5+ B clonal subpopulation.

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