Open AccessStatistical Test/Estimation Methods Used in Contemporary Phase III Cancer Randomized Controlled Trials with Time‐to‐Event Outcomes
Author(s) -
Uno Hajime,
Horiguchi Miki,
Hassett Michael J.
Publication year - 2020
Publication title -
the oncologist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.176
H-Index - 164
eISSN - 1549-490X
pISSN - 1083-7159
DOI - 10.1634/theoncologist.2019-0464
Subject(s) - medicine , estimation , clinical trial , randomized controlled trial , event (particle physics) , test (biology) , cancer , statistical analysis , intensive care medicine , medical physics , statistics , surgery , paleontology , physics , management , mathematics , quantum mechanics , economics , biology
There exist a wide variety of statistical methods for clinical trials. Despite decades of clinical trial research, little is known about which methods are used in data analysis practice of the real world. This review describes the evidence of existing practices on survival data analysis and identifies potential opportunities to improve them.