Open AccessA Case of Donor‐Transmitted Non‐Small Cell Lung Cancer After Liver Transplantation: An Unwelcome Guest
Author(s) -
Sonbol Mohamad B.,
Halling Kevin C.,
Douglas David D.,
Ross Helen J.
Publication year - 2019
Publication title -
the oncologist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.176
H-Index - 164
eISSN - 1549-490X
pISSN - 1083-7159
DOI - 10.1634/theoncologist.2018-0517
Subject(s) - medicine , malignancy , lung cancer , cancer , organ donation , transplantation , organ transplantation , liver transplantation , liver cancer , lung , pathology , oncology , radiology , surgery
Cancer transmission with organ donation has been previously reported with a variety of malignancies and organ transplants. The risk of transmission through organ transplantation from donors with a history of previously treated malignancies has been addressed by guidelines from transplant societies. Herein, we report a case of a patient who developed lung cancer confined to the liver after liver transplantation with no known history of malignancy in the donor. The suspicion of donor origin arose after positron emission tomography‐computerized tomography scan showed metastatic lung cancer only involving the transplanted liver without a primary focus. Genetic analysis of the malignant cells confirmed donor origin of the cancer.