Open Access(Iso‐)form Matters: Differential Implication of Vav3 Variants in Ovarian Cancer
Author(s) -
Boesch Maximilian,
Reimer Daniel,
Sopper Sieghart,
Wolf Dominik,
Zeimet Alain G.
Publication year - 2018
Publication title -
the oncologist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.176
H-Index - 164
eISSN - 1549-490X
pISSN - 1083-7159
DOI - 10.1634/theoncologist.2017-0683
Subject(s) - medicine , context (archaeology) , malignancy , cancer , ovarian cancer , differential (mechanical device) , bioinformatics , computational biology , cancer research , pathology , biology , paleontology , engineering , aerospace engineering
This commentary discusses recent results on the role of Vav3 in malignancy, in an effort to begin to define the underlying mechanisms and tissue context by which Vav3 proteins, in particular Vav3.1, promote the progression of malignant diseases and further modulate the response to clinically relevant drugs.