Open AccessDevelopment of Molecularly Driven Targeted Combination Strategies
Author(s) -
Yap Timothy A.,
Rodon Jordi
Publication year - 2017
Publication title -
the oncologist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.176
H-Index - 164
eISSN - 1549-490X
pISSN - 1083-7159
DOI - 10.1634/theoncologist.2017-0402
Subject(s) - medicine , targeted therapy , isolation (microbiology) , intensive care medicine , cancer , bioinformatics , biology
Targeted therapies are often inadequate when used in isolation as single agents. Combining diverse targeted therapies could optimally impact patient care by overcoming cancer resistance mechanisms. This commentary highlights such combinatorial strategies, including discussion on a recent trial.