Open AccessBridging the Gap Between Sorafinib Efficacy and Effectiveness in Advanced Hepatocellular Carcinoma
Author(s) -
Nipp Ryan,
Goyal Lipika
Publication year - 2016
Publication title -
the oncologist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.176
H-Index - 164
eISSN - 1549-490X
pISSN - 1083-7159
DOI - 10.1634/theoncologist.2016-0349
Subject(s) - medicine , generalizability theory , bridging (networking) , observational study , hepatocellular carcinoma , clinical trial , population , oncology , medical physics , environmental health , computer network , statistics , mathematics , computer science
In this editorial, the generalizability of trial results to the geriatric population is discussed. Specifically, the results from a recent observational study are compared with results from the SHARP trial, and recommendations are made for bridging the gap between efficacy and effectiveness in clinical research, particularly with regard to older patients.