Open AccessTherapeutic potential of traditional Chinese medicine for vascular endothelial growth factor
Author(s) -
Yijia Mao,
Lingkai Meng,
Huayi Liu,
Yuting Lu,
Kuo Yang,
Guangze Ouyang,
Yanran Ban,
Shuang Chen
Publication year - 2022
Publication title -
journal of zhejiang university. science b
Language(s) - English
Resource type - Journals
eISSN - 1862-1783
pISSN - 1673-1581
DOI - 10.1631/jzus.b2101055
Subject(s) - traditional chinese medicine , vascular endothelial growth factor , angiogenesis , regulator , medicine , vegf receptors , pathological , clinical practice , function (biology) , growth factor , traditional medicine , neuroscience , alternative medicine , biology , pathology , family medicine , microbiology and biotechnology , biochemistry , gene , receptor
Vascular endothelial growth factor (VEGF) is the main regulator of physiological angiogenesis during embryonic development, bone growth, and reproductive function, and it also participates in a series of pathological changes. Traditional Chinese medicine (TCM), with a history of more than 2000 years, has been widely used in clinical practice, while the exploration of its mechanisms has only begun. This review summarizes the research of recent years on the influence of TCM on VEGF. It is found that many Chinese medicines and recipes have a regulatory effect on VEGF, indicating that Chinese medicine has broad prospects as a complementary and alternative therapy, providing new treatment ideas for clinical applications and the theoretical basis for research on the mechanisms of TCM.