Genetic Interactions in Nonsyndromic Orofacial Clefts in Europe—EUROCRAN Study | Zendy

Peter Mossey | Zendy; Julian Little | Zendy; Régine P.M. SteegersTheunissen | Zendy; Anne M. Molloy | Zendy; Borut Peterlin | Zendy; William C. Shaw | Zendy; Candice Y. Johnson | Zendy; David Fitzpatrick | Zendy; Paola Franceschelli | Zendy; Michele Rubini | Zendy

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Genetic Interactions in Nonsyndromic Orofacial Clefts in Europe—EUROCRAN Study

Author(s) -

Peter Mossey,

Julian Little,

Régine P.M. SteegersTheunissen,

Anne M. Molloy,

Borut Peterlin,

William C. Shaw,

Candice Y. Johnson,

David Fitzpatrick,

Paola Franceschelli,

Michele Rubini

Publication year - 2016

Publication title -

the cleft palate-craniofacial journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.641

H-Index - 79

eISSN - 1545-1569

pISSN - 1055-6656

DOI - 10.1597/16-037

Subject(s) - medicine , methylenetetrahydrofolate reductase , genotype , relative risk , confidence interval , genetics , pregnancy , gene , pediatrics , biology

Nonsyndromic cleft lip with or without cleft palate (nsCL±P) and nonsyndromic cleft palate (nsCP) are caused by a combination of genetic and environmental risk factors. We investigated gene-environment and gene-gene joint effects in a large multicenter study of case-parent triads.

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