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Possible Ergotamine‐Caffeine—Associated Delirium
Author(s) -
Gulbranson Scott H.,
Mock Roy E.,
Wolfrey Jeffrey D.
Publication year - 2002
Publication title -
pharmacotherapy: the journal of human pharmacology and drug therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.227
H-Index - 109
eISSN - 1875-9114
pISSN - 0277-0008
DOI - 10.1592/phco.22.1.126.33500
Subject(s) - ergotamine , caffeine , delirium , migraine , confusion , medicine , anesthesia , psychiatry , psychology , psychoanalysis
An elderly patient with a history of chronic migraine was hospitalized with systolic hypertension and significant mental status changes, including increasing confusion, combative behavior, and remarkably detailed auditory hallucinations of several weeks' duration. Daily increased consumption of a product containing ergotamine 1 mg and caffeine 100 mg coincided with both onset and increasing severity of symptoms. To our knowledge, this is the first case reported in the contemporary literature of severe mental status changes and hallucination possibly due to ergotamine‐caffeine.