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Vasopressin and Blood Pressure Support for Pancreatitis‐Induced Systemic Inflammatory Response Syndrome with Circulatory Shock
Author(s) -
Lamarre Patrice,
Perreault Brigitte,
Lesur Olivier
Publication year - 2001
Publication title -
pharmacotherapy: the journal of human pharmacology and drug therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.227
H-Index - 109
eISSN - 1875-9114
pISSN - 0277-0008
DOI - 10.1592/phco.21.5.506.34494
Subject(s) - vasopressin , medicine , norepinephrine , shock (circulatory) , circulatory system , blood pressure , systemic inflammatory response syndrome , septic shock , acute pancreatitis , epinephrine , pancreatitis , anesthesia , cardiology , sepsis , dopamine
A 54‐year‐old patient, admitted to the intensive care unit with a diagnosis of severe pancreatitis, developed circulatory shock that failed to respond to standard vasopressor treatment: epinephrine and norepinephrine. Addition of vasopressin helped reduce standard catecholamine need while maintaining adequate arterial blood pressure. Vasopressin appears to be a promising agent for maintaining arterial pressure during septic shock or systemic inflammatory response syndrome, but due to limited data and potential side effects, its use as first‐line treatment for these indications is not recommended.