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Diabetes Mellitus Associated with Clozapine Therapy
Author(s) -
Wehring Heidi,
Alexander Bruce,
Perry Paul J.
Publication year - 2000
Publication title -
pharmacotherapy: the journal of human pharmacology and drug therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.227
H-Index - 109
eISSN - 1875-9114
pISSN - 0277-0008
DOI - 10.1592/phco.20.9.844.35201
Subject(s) - clozapine , medicine , diabetes mellitus , exacerbation , antipsychotic , atypical antipsychotic , adverse effect , pediatrics , schizophrenia (object oriented programming) , psychiatry , endocrinology
Clozapine is an atypical antipsychotic that is associated with certain adverse effects that limit its usefulness. Published case reports have associated clozapine with impairment of glucose tolerance, including the onset or exacerbation of diabetes mellitus. We report two patients who experienced diabetes mellitus associated with the agent.