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Corticosteroids and Serious Cytarabine‐Induced Pulmonary Edema
Author(s) -
Larouche Geneviève,
Denault André,
Prénovault Julie
Publication year - 2000
Publication title -
pharmacotherapy: the journal of human pharmacology and drug therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.227
H-Index - 109
eISSN - 1875-9114
pISSN - 0277-0008
DOI - 10.1592/phco.20.17.1396.34897
Subject(s) - cytarabine , medicine , respiratory distress , daunorubicin , pulmonary edema , acute respiratory distress , chemotherapy , respiratory failure , anesthesia , leukemia , gastroenterology , lung
A woman with acute leukemia receiving induction chemotherapy with conventional doses of cytarabine (ARA‐C) 200 mg/m 2 /day and daunorubicin 45 mg/m 2 /day developed acute respiratory distress syndrome. Respiratory failure was attributed to ARA‐C primarily by exclusion and radiographic findings. She was weaned rapidly from the ventilator after receiving steroid therapy.