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Amiodarone‐Induced Pulmonary Toxicity
Author(s) -
Kanji Zahra,
Sunderji Rubina,
Gin Kenneth
Publication year - 1999
Publication title -
pharmacotherapy: the journal of human pharmacology and drug therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.227
H-Index - 109
eISSN - 1875-9114
pISSN - 0277-0008
DOI - 10.1592/phco.19.18.1463.30890
Subject(s) - amiodarone , medicine , chest radiograph , pulmonary toxicity , pulmonary function testing , adverse effect , toxicity , cardiology , intensive care medicine , lung , anesthesia , atrial fibrillation
Amiodarone‐induced pulmonary toxicity (AIPT) is one of the most serious adverse effects of amiodarone therapy and can be fatal. Therefore, vigilant monitoring is advised. Baseline chest radiograph and pulmonary function tests and follow‐up chest films at 3‐month intervals are advocated. However, since abnormalities on these two examinations do not always precede symptoms, patient self‐reports of respiratory symptoms appear to be the best method for early detection of AIPT.