Premium
Trimethoprim‐Sulfamethoxazole‐Induced Tremor in an Immunocompetent Patient
Author(s) -
Patterson Robert G.,
Couchenour Rachel L.
Publication year - 1999
Publication title -
pharmacotherapy: the journal of human pharmacology and drug therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.227
H-Index - 109
eISSN - 1875-9114
pISSN - 0277-0008
DOI - 10.1592/phco.19.18.1456.30903
Subject(s) - medicine , trimethoprim , sulfamethoxazole , adverse effect , antibiotics , hypersensitivity reaction , drug , dermatology , pharmacology , microbiology and biotechnology , biology
Trimethoprim‐sulfamethoxazole (TMP‐SMX) is a widely administered antibiotic that is well tolerated by most patients. Hypersensitivity reactions and gastrointestinal intolerance are the most common adverse events associated with it. Central nervous system adverse effects such as tremors are less common and occur primarily in patients with acquired immune deficiency syndrome. A 29‐year‐old immunocompetent man developed a tremor while taking TMP‐SMX. The tremor resolved within 2 days after the drug was discontinued.