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Antimicrobial Resistance in Gram‐Positive Bacteria: The Myth of the MIC
Author(s) -
Rapp Robert P.
Publication year - 1999
Publication title -
pharmacotherapy: the journal of human pharmacology and drug therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.227
H-Index - 109
eISSN - 1875-9114
pISSN - 0277-0008
DOI - 10.1592/phco.19.12.112s.31703
Subject(s) - antimicrobial , bacteria , microbiology and biotechnology , minimum inhibitory concentration , antibiotic resistance , gram negative bacteria , biology , antibiotics , escherichia coli , genetics , gene
Although much progress has occurred in the fight to treat infection, resistant bacteria increasingly are becoming problematic. The minimum inhibitory concentration is easily determined, yet its definition, clinical application, and relevance are confusing. In addition, errors can occur during in vitro susceptibility testing. The mechanism of resistance for different organisms is discussed as are the pitfalls of susceptibility testing and the prescription of antimicrobial agents.